Healing from within,
from salmon DNA,
to your skin.
Rejuran is a salmon-derived polynucleotide (PN) injectable that triggers deep skin regeneration — healing micro-damage, rebuilding collagen, and refining texture. Developed in Korea, it is the original "skin healing injection" now used worldwide.
At a glance.
- Treatment time
- 15–25 minutes
- Results visible
- 2–3 weeks
- Duration
- 6–9 months per cycle
- Downtime
- 24 hours
- Sessions needed
- 3–4 (2-week intervals)
- Price range
- ₩150,000 – ₩350,000 per session
What is Rejuran?
Not filler. Not botox. A healer.
Rejuran is a skin booster made from purified polynucleotides (PN) derived from salmon DNA. Unlike filler (which adds volume) or botox (which freezes muscles), Rejuran activates your skin's own repair mechanism — stimulating fibroblasts to rebuild collagen, elastin, and hyaluronic acid naturally. The result: improved texture, elasticity, and reduced fine lines over 3 months. At JRYN Seomyeon, we offer standard Rejuran, Healer (advanced face formula), and Eye (under-eye specialized).
"A great nose isn't bigger or smaller — it's
in proportion with your face.
"
Dr. Lee · 15+ years in regenerative dermatology
Consultation Photo · 4:5
The science
,
simplified.
Understanding the mechanism helps you set realistic expectations and choose the right brand for your goals.
Skin condition diagnosis
Dr. Lee assesses skin damage, sensitivity, post-acne marks, and overall skin quality. Rejuran is ideal for damaged or sensitive skin needing regeneration, not volume.
Topical numbing
Numbing cream is applied for 15 minutes before treatment. Most fillers also contain lidocaine, so injection discomfort is minimal.
Multi-point injection
Rejuran injected at multiple shallow points across face — typically 60–80 injection points per session. Polynucleotides stimulate fibroblasts to repair and renew skin.
Instant result, 2-week settling
Results are visible immediately. Minor swelling and firmness resolves over 1–2 weeks, revealing the final natural-looking contour. Effect lasts 12–18 months.
From consultation
to confidence.
Most foreign patients complete the entire experience — consultation, treatment, and a brief aftercare check — in a single afternoon.
Photo · 1:1
Consultation
15-minute analysis with Dr. Lee. Facial measurement, brand selection, honest expectation-setting. No pressure to proceed same day.
Photo · 1:1
Treatment
15-minute procedure with topical numbing. Cannula technique for safety. Real-time mirror feedback so you see the result building.
Photo · 1:1
Aftercare
Multilingual aftercare instructions. WhatsApp support for your entire stay. Optional 2-week video follow-up included.
Where we inject
,
and why.
Each area has its own anatomical target, typical volume, and result timeline. Dr. Lee will recommend a personalized plan during consultation.
| Treatment Area | Concern Addressed | Typical Dose | Visible In |
|---|---|---|---|
| Full face | Overall texture, dullness, aging | 2ml per session | 2–3 weeks |
| Cheeks | Pore size, laxity | 1ml per side | 3–4 weeks |
| Forehead | Fine lines, dry texture | 0.5–1ml | 2–3 weeks |
| Neck | Crepey skin, lines | 1–2ml | 4–6 weeks |
| Décolletage | Sun damage, fine wrinkles | 1–2ml | 4–6 weeks |
Korean & imported
,
side by side.
Both Korean and imported filler brands are clinically safe when administered by licensed dermatologists. Differences come down to cost, longevity, and specific properties.
| Brand | Price | Best For | Duration |
|---|---|---|---|
| Korea Rejuran (Standard PN) | ₩150,000 | First-timers, overall skin quality | 6–9 months |
| Korea Rejuran S (Scar) | ₩250,000 | Acne scars, skin texture irregularity | 6–9 months |
| Korea Rejuran HB+ (Hydro) | ₩300,000 | Deep hydration with HA blend | 6–9 months |
| Korea Rejuran I (Eye) | ₩350,000 | Under-eye dark circles, fine lines | 6–9 months |
Good candidates &
who should wait.
Every treatment has ideal candidates and situations where it's not recommended. Safety first — always.
Good candidates
- Dull, tired-looking skin wanting natural glow
- Early signs of aging (late 20s to early 40s)
- Acne scars or uneven skin texture
- Want regeneration rather than temporary volume
- Prefer natural-looking gradual results
Not ideal for
- Active skin infections or inflammation
- Fish or salmon allergy (PN is salmon-derived)
- Autoimmune conditions (consult physician first)
- Pregnant or breastfeeding
- Want instant dramatic results (try filler instead)
Before & after.
What happens after.
We believe in informed patients. Here's what to expect after treatment, and the full safety profile.
After your treatment
- Avoid touching or washing the area for 6 hours
- Small bumps at injection sites are normal — resolve within 24 hours
- No makeup for 12 hours
- No saunas, hot yoga, or intense exercise for 48 hours
- Apply gentle moisturizer and SPF 50+ starting day 2
- Avoid retinol, acids, or chemical exfoliation for 7 days
- Visible improvement by 2–3 weeks; peak result at 8–12 weeks
Possible side effects
- Mild swelling at bridge (2–3 days)
- Small bruising (resolves within a week)
- Tightness or firmness when smiling (2 weeks)
- Tiny redness at injection points (24 hours)
- Vascular occlusion (extremely rare with proper technique; Dr. Lee uses cannula to minimize risk)
- Tyndall effect — bluish tint from superficial placement (correctable)
- Asymmetric swelling (resolves as filler settles)
- Infection at injection site (very rare with sterile technique)
Dr. Lee Portrait
Dr. Jeong Heon Lee,
board-certified
dermatologist.
Every face has its own quiet rhythm.
My work is to add precision without erasing what's natural
—
revealing what already makes you beautiful,
in its most graceful form. A journey we walk together.
- MD, Inje University College of Medicine
- Member, Korean Dermatological Association
- Member, Korean Society of Cosmetic Dermatology
- 15+ years in cosmetic dermatology
A space designed
for foreign patients.
Located 3 minutes from Seomyeon Station. English signage, multilingual staff, and consultation rooms designed to feel like a private studio rather than a hospital.
Main Photo · 4:3
"We designed every consultation room to feel calm, unhurried, and private — the way decisions about your face deserve to be made."
JRYN · Seomyeon, Busan